Empagliflozin is a prescription medicine used to treat type 2 diabetes. Type 2 diabetes is a condition where the body does not make enough insulin, or the insulin that it makes does not work properly. This can cause high blood sugar levels (hyperglycemia). It may be prescribed if diet and exercise alone are not enough to manage blood sugar or if other diabetes medicines like metformin cannot be used. Empagliflozin can also be used to treat heart failure by reducing the risk of the heart becoming weaker and helping with symptoms like tiredness. As the leader of Empagliflozin Impurities Manufacturer, Aquigen Bio is here to help you understand Empagliflozin in detail. Let’s begin!
Treating Type 2 Diabetes
The primary use of empagliflozin is for the treatment of type 2 diabetes. Type 2 diabetes occurs when the body becomes resistant to insulin or does not produce enough insulin. This causes blood sugar levels to rise. Empagliflozin works by inhibiting sodium-glucose cotransporter-2 (SGLT2) in the kidneys. SGLT2 is responsible for reabsorbing glucose back into the bloodstream. By blocking SGLT2, empagliflozin prevents glucose reabsorption and instead encourages glucose to be removed from the body through urine. This lowers high blood sugar levels.
Empagliflozin can be used alone if diet and exercise changes are not enough to control blood sugar. It may also be prescribed with other diabetes medications like insulin to help provide better blood sugar control when a single drug does not work adequately. Some branded combinations of empagliflozin with other antidiabetic drugs are available which combine empagliflozin with metformin, and some combine empagliflozin with linagliptin.
Treating Heart Failure
In addition to controlling blood sugar, empagliflozin is approved for use in reducing the risk of cardiovascular death and the worsening of heart failure in adults with heart failure. Studies have shown empagliflozin can reduce the risk of a person’s heart becoming weaker or the progression of heart failure. It may help improve symptoms like excessive tiredness in heart failure patients. The exact mechanism by which empagliflozin benefits heart failure is not fully understood but may involve lowering blood pressure and reducing stress on the heart through its glucose-lowering effects.
Dosage and Administration
Empagliflozin is available as oral tablets that are taken once daily, usually in the morning with or without food. The standard dosage is 10mg or 25mg daily depending on the individual’s kidney function and response to treatment. It may take 1-2 weeks to see glucose-lowering effects but the full benefits can take up to 1 week to be apparent. If empagliflozin is combined with other diabetes drugs, there is a risk of hypoglycemia or low blood sugar, so patients should carry something sugary like candy or fruit juice in case blood sugar drops too low. Unlike some other diabetes medications, empagliflozin does not typically cause weight gain and may promote weight loss in some individuals.
Side Effects
Overall empagliflozin is generally well tolerated but some potential side effects can include:
- Genital fungal infections like yeast infection
- Urinary tract infections
- Increased urination
- Low blood sugar (in combination with other drugs that lower glucose)
- Low blood pressure and dizziness
- Volume depletion (loss of too much fluid from the body)
- Constipation
- Nausea
- Male reproductive organ infections
Rare but serious side effects could potentially include ketoacidosis (buildup of ketones in the blood), serious urinary tract infections and skin and soft tissue infections of the genital area. Anyone experiencing severe side effects should contact their doctor.
Conclusion
In conclusion, Empagliflozin helps your body remove excess sugar through urine and is used to control blood sugar levels for people with type 2 diabetes. Empagliflozin impurities manufacturers like Aquigen Bio Sciences specialize in providing high-quality empagliflozin impurities and synthetic intermediates to support pharmaceutical R&D for new drugs. As one of the leading empagliflozin impurities suppliers in India, Aquigen utilizes expertise in organic synthesis and analytical characterization to develop optimized synthesis routes for pure research-grade empagliflozin and related compounds. This helps accelerate the development of new medicines for treating chronic diseases like diabetes and heart failure. If you require Empagliflozin impurities, get in touch with us. We are here to meet all your empagliflozin needs!