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Balsalazide Disodium

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CAT NO

AQ-B000509

CAS NO

213594-60-6

Mol.F

C17H13N3O6 : 2(Na)

Mol.Wt

355.31 : 2(23.0)

Availability

In Stock

Chemical name

Disodium (E)-5-((4-((2-carboxyethyl)carbamoyl)phenyl)diazenyl)-2-hydroxybenzoic acid

Rel. CAS No

80573-04-2 (free base) ; 150399-21-6 (Disodium Dihydrate Salt)

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Balsalazide Disodium


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Product Description

Balsalazide Disodium is a high-quality reference standard supplied with comprehensive characterization data, ensuring compliance with regulatory guidelines. This product is essential for analytical method development, method validation (AMV), quality control (QC) applications, and plays a crucial role in Abbreviated New Drug Applications (ANDA).

Balsalazide Disodium can be used as a reference standard, with possible traceability to pharmacopeial standards such as USP or EP, based on feasibility. AquigenBio products are strictly for analytical purposes and is not intended for human use.

Applications

Balsalazide Disodium is primarily used in:

  1. Pharmaceutical R&D and Regulatory Support

    • Used as a reference standard for method validation, impurity profiling, and assay development

    • Relevant for ANDA, DMF, and pharmacopoeial submissions

  2. Analytical Chemistry

    • Applied in HPLC, LC-MS/MS, and stability studies

    • Supports analytical method validation (AMV) and development of specifications

  3. Drug Formulation & Quality Control

    • Studied as a 5-ASA (5-aminosalicylic acid) prodrug used in inflammatory bowel diseases (e.g. ulcerative colitis)

    • Relevant in controlled release formulation research

  4. Research & Academia

    • Investigated in drug metabolism, prodrug activation, and GI targeting mechanisms

Safety & Handling Information for Chemical Products

1. Read the Safety Data Sheet (SDS) : The SDS contains important safety information for handling procedures, first-aid measures, disposal instructions, etc. Read it carefully.

2. Wear Personal Protective Equipment (PPE) : Always wear PPE as indicated in the SDS and by the manufacturer. This may include safety goggles, gloves, lab coats, respirators, and protective clothing.

3. Handle with Care : Be careful with chemical products - prevent spills, splashes, or inhaling fumes or dust. Use secondary trays or spill kits during chemical transfer or dispensing.

4. Work in a Well-Ventilated Area : Use chemical products in well-ventilated spaces to reduce vapour or gas exposure. Indoors, ensure ample ventilation via mechanical systems, fume hoods, or open windows and doors.

5. Avoid Mixing Chemicals : Avoid mixing chemical products unless directed by the manufacturer or a qualified professional. Incompatible mixes can lead to hazardous reactions, toxic gas releases, or explosions.

6. Labeling and Storage : Label chemical containers with product names, hazards, and handling information. Store in original or approved containers.

7. Prevent Contamination : Prevent cross-contamination with dedicated equipment or thorough decontamination. Keep food, drinks, and personal items away from chemical storage or work zones.

8. Emergency Procedures : Learn emergency procedures for spills, leaks, fires, or exposure incidents. Keep spill control materials, fire extinguishers, and emergency eyewash/shower facilities accessible.

9. First Aid : Know first aid for chemical exposure (eye contact, skin contact, inhalation, and ingestion). Ensure accessible supplies and trained personnel for assistance.

10. Proper Waste Disposal : Ensure chemical waste disposal as per local regulations; segregate hazardous from non-hazardous waste for health and environmental protection.

11. Training and Education : Offer thorough training to chemical handlers, covering usage, hazards, safety, and emergency response.

12. Report Incidents and Near Misses : Report incidents, near misses, spills, or safety concerns promptly to authorities and supervisors for investigation and action. By following these safety and handling guidelines, you can minimize risks associated with chemical products and create a safer work environment for yourself and others.

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Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

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